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Tina Izard Selected Research

metavinculin

1/2021The Cryogenic Electron Microscopy Structure of the Cell Adhesion Regulator Metavinculin Reveals an Isoform-Specific Kinked Helix in Its Cytoskeleton Binding Domain.
10/2012The metavinculin tail domain directs constitutive interactions with raver1 and vinculin RNA.
12/2010Improving the diffraction of full-length human selenomethionyl metavinculin crystals by streak-seeding.
5/2010A helix replacement mechanism directs metavinculin functions.

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Tina Izard Research Topics

Disease

12Neoplasms (Cancer)
12/2021 - 07/2011
3Breast Neoplasms (Breast Cancer)
01/2021 - 01/2017
3Cardiovascular Diseases (Cardiovascular Disease)
02/2016 - 10/2012
2Neurofibromatosis 2 (Neurofibromatosis Type II)
12/2021 - 01/2018
2Cardiomyopathies (Cardiomyopathy)
01/2021 - 05/2010
2Neoplasm Metastasis (Metastasis)
08/2020 - 10/2018
2Hepatocellular Carcinoma (Hepatoma)
12/2013 - 01/2009
2Dilated Cardiomyopathy (Cardiomyopathy, Congestive)
10/2012 - 12/2010
1Atrophy
01/2021
1Insulin Resistance
01/2021
1Muscular Atrophy (Muscle Atrophy)
01/2021
1Tuberculosis (Tuberculoses)
01/2021
1Pathologic Processes
08/2020
1Thrombosis (Thrombus)
08/2020
1Intellectual Disability (Idiocy)
01/2020
1Viremia
01/2019
1Hemorrhage
10/2018
1Heart Failure
01/2016
1Primary Myelofibrosis (Myelosclerosis)
12/2013
1Liver Cell Adenoma (Hepatocellular Adenoma)
01/2009
1Bacillary Dysentery (Shigellosis)
11/2006
1Rheumatoid Arthritis
10/2002
1Autoimmune Diseases (Autoimmune Disease)
10/2002

Drug/Important Bio-Agent (IBA)

5Proteins (Proteins, Gene)FDA Link
12/2021 - 11/2006
4metavinculinIBA
01/2021 - 05/2010
4LigandsIBA
01/2021 - 01/2009
4VinculinIBA
02/2016 - 10/2012
3Neurofibromin 2 (Merlin)IBA
12/2021 - 12/2011
3IntegrinsIBA
08/2020 - 10/2018
3Interleukin-6 (Interleukin 6)IBA
12/2013 - 01/2009
2EnzymesIBA
12/2021 - 01/2021
2Pharmaceutical PreparationsIBA
01/2019 - 12/2018
1Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA
12/2021
1Phosphotransferases (Kinase)IBA
12/2021
1Long-Acting Thyroid Stimulator (LATS)IBA
12/2021
1Tumor Suppressor Proteins (Proteins, Tumor Suppressor)IBA
12/2021
1pantetheine-phosphate adenylyltransferaseIBA
01/2021
1GlucocorticoidsIBA
01/2021
1Glucose (Dextrose)FDA LinkGeneric
01/2021
1Estrogen ReceptorsIBA
01/2021
1Cell Adhesion MoleculesIBA
01/2020
1Cadherins (E-Cadherin)IBA
01/2020
1Biological ProductsIBA
10/2018
1LipidsIBA
01/2018
1CytokinesIBA
03/2017
1Hormones (Hormone)IBA
01/2017
1Estrogens (Estrogen)FDA Link
01/2017
1Estrogen Receptor alphaIBA
01/2017
1Tyrosine Kinase InhibitorsIBA
12/2013
1ruxolitinibIBA
12/2013
1moesinIBA
12/2011
1ezrinIBA
12/2011
1radixinIBA
12/2011
1Cytokine Receptor gp130IBA
07/2011
1STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA
01/2009
1beta CateninIBA
01/2009
1Histocompatibility Antigens Class IIIBA
10/2002
1HLA-DR4 Antigen (HLA DR4 Antigen)IBA
10/2002
1HLA-DR1 Antigen (HLA DR1 Antigen)IBA
10/2002
1CollagenIBA
10/2002
1Peptides (Polypeptides)IBA
10/2002

Therapy/Procedure

4Therapeutics
01/2021 - 01/2017